I-Spermidine Powder: Ingabe Ifanelekile i-Hype?
Umzimba womuntu wakhiwa izitho nezicubu, nazo ezakhiwa yizingxenye zokusebenza zomzimba, okungukuthi amaseli. Cishe zonke izinqubo zebhayoloji ziyenziwa futhi zigcinwe ezingeni lamangqamuzana, futhi imiphumela yalokhu icatshangelwa kwizicubu nezitho zomzimba. Ukuqala ngamaseli ama-stem, amangqamuzana omuntu kuyo yonke inqubo yokuthuthuka ngesikhathi sombungu ayahluka abe ngamaseli ahlukahlukene afudukela ezingxenyeni ezihlukene zomzimba futhi enze imisebenzi ehlukile ngokufanele.Amaseli enza imisebenzi ehlukahlukene efana ne-metabolism ne-homeostasis, kepha-ke, awanakukwazi ukuzenzela wona futhi adinga amakhemikhali ahlukile, ama-enzyme, kanye nokusayinwa kwamakhemikhali okubasiza ukufeza imiphumela abayifunayo.
Izinhlobo ezahlukahlukene zamaseli zinesikhathi sokuphila esehlukile futhi uma nje eseqede leso sikhathi, angena ebusosheni noma ebudaleni, bezinhlobo, ngemuva kwalokho ziyadilizwa noma zehliswe, okukhomba ukuphela kwempilo yazo.
Njengokuguga, imisebenzi yamaselula iguqulwa kuqala, okuholele ezimpawu zomzimba zokuguga, ekugcineni. Kodwa-ke, kwenziwa izinhlobo eziningi zocwaningo ukutadisha nokuqonda ukuthi ungayikhulisa kanjani impilo yamaseli futhi ngenxa yalokho, abantu. Njengomphumela walezi zifundo, kwatholakala i-ejenti yokuphila isikhathi eside futhi eyenzeka njengenye yezakhi eziyinhloko ezibalulekile ekugcineni imisebenzi ehlukene yamaseli. Le nhlanganisela itholakala ngobuningi emzimbeni womuntu futhi ibizwa nge-spermidine.
Ukwenza ngcono impilo yomuntu nokukhuthaza isikhathi sokuphila esandisiwe samaseli, futhi ngenxa yalokho, umuntu, kungumsebenzi ophambili wale nhlanganisela, yize ibamba iqhaza ekuphenduleni kwamakhemikhali nokwakheka komzimba emzimbeni.
Yini i-Spermidine Powder?
I-Spermidine iyi-polyamine etholakala ngokwemvelo ebalulekile ekusebenzeni okujwayelekile komzimba wonke. Yize ingabambi iqhaza ekulondolozeni noma ekukhiqizeni isidoda, ibizwa nge-spermidine compound ngoba yaqale yatholwa kwisidoda. Ihlanganiswe emzimbeni womuntu ngezenzo ze-enzyme, i-spermidine synthase ekhoneni, i-putrescine.I-Spermidine ingaqhutshekelwa phansi ibe yi-spermine, namanye ama-polyamine, kufaka phakathi i-isomer yesakhiwo se-spermine, i-thermospermine. Kutholakale kuma-ribosomes weseli, umsebenzi oyinhloko wale nhlanganisela ukukhuthaza i-autophagy evumela ukuthi ukuvuselelwa kweseli kwenzeke emzimbeni womuntu. Iyakwazi ukwenza le misebenzi ngokunciphisa ukuzilimaza komzimba ezingeni lamaselula emzimbeni, hhayi emazingeni aphezulu.
Njengoba kunikezwe indima enkulu edlalwa yi-spermidine emzimbeni, ukuphatha amazinga ayo ejwayelekile kufanele kubaluleke. Kodwa-ke, kwatholakala ukuthi amazinga e-Spermidine emzimbeni aqala ukwehla njengoba umuntu eneminyaka eyodwa, okunganciphisa ukusebenza kahle okwenziwa ngemisebenzi ehlukile ye-metabolic. Konke lokhu kubangela ukwehla kwamakhono omzimba womuntu okuvame ukusolwa ngokuguga, kepha akusikho ukuguga ngqo okukubangelayo kepha kunalokho umphumela wokwehliswa kwamakhemikhali abalulekile emzimbeni womuntu.
I-Spermidine powder iyindlela yokwengeza exogenous yeSpermidine ehlose ukugcwalisa izitolo zomzimba zale-aliphatic polyamine futhi ithuthukise ukusebenza komzimba.
Umlando we-Spermidine
I-Spermidine ibizwa kanjalo ngoba ekuqaleni yayihlukaniswe nesidoda kepha kusukela lapho kutholakale ukuthi isatshalaliswa kabanzi emzimbeni womuntu futhi idlala izindima ezahlukahlukene ezingxenyeni ezihlukene zomzimba. Yize kubalulekile ukuthi wazi ukuthi unomsebenzi owodwa oyinhloko emzimbeni wonke owanda kwamangqamuzana nokuvuselelwa, ngokukhuthaza ukuzilimaza komzimba. Ingenye yezinto ezisebenza isikhathi eside kubantu nakwezinye izilwane ezincelisayo.I-ejenti yokuphila isikhathi eside yatholwa esidunjini somuntu ngu-Antoni van Leeuwenhoek, ngo-1678 yize ayichaza nje ngokuthi amakristalu. Kwaze kwaba yiminyaka ecishe ibe ngama-200 kamuva lapho kwatholakala ukuthi amakristalu abonwa nguLeeuwenhoek kwakuyi-spermine, owalandela iSpermidine. Kodwa-ke, ukwakheka kwamakhemikhali kwe-spermidine ne-spermine kwakungaziwa futhi kwaze kwaba ngo-1924 lapho ukwakheka kwamakhemikhali kwatholakala futhi kwafundwa ngokuningiliziwe.
Ukuqhubeka nokufunda ngesakhiwo se-spermidine kuveze okuningi ngemisebenzi yaso nezici ezithile emzimbeni womuntu. Kutholakale ukuthi i-spermidine, njengayo yonke i-polyamine, iyinhlanganisela ezinzile engaqedi noma isabele ezindaweni ezine-asidi noma eziyisisekelo. Ngaphezu kwalokho, i-spermidine itholwe inenkokhelo enhle evumela ukuthi ibophele kuma-molecule akhokhiswe kabi njenge-RNA ne-DNA.
Ngaphezu kwalokho, iSpermidine itholakale itholakala ngobuningi emzimbeni womuntu, kanti amazinga aqala ukwehla njengobudala obubodwa, ngesikhathi esifanayo namazinga e-collagen nama-elastin nawo azoncipha. Esigabeni sokuqala sempilo, abantu bathola i-spermidine ngobisi lwebele noma ifomula lengane futhi njengoba bekhula, bathola i-spermidine emithonjeni ehlukahlukene yokudla. Kodwa-ke, imithombo engaphandle yemvelo ye-spermidine ayenele ukugcwalisa izitolo zenkompo ezikhishwa ngenxa yokwehla kokukhiqizwa kwe-polyamine.
Ezimweni ezinjalo, kwenziwa izinhlobo eziningana zocwaningo ukuhlaziya ukuthi izitolo zingagcwaliswa kanjani futhi izithako zeSpermine eziqukethe i-Spermidine trihydrochloride powder njengesithako esisebenzayo kwatholakala ukuthi ziyisixazululo sale nkinga. Izithako zeSpermidine manje sezitholakala kalula futhi zamukelwa kabanzi njengezithasiselo zokuphila isikhathi eside.
Umsebenzi weSpermidine eMzimbeni Womuntu
Izithako ze-Spermidine zidlala izindima ezifanayo ne-spermidine emzimbeni, yingakho kubalulekile ukwazi imisebenzi esemqoka ye-Spermidine emzimbeni womuntu. I-Spermidine itholakala ibalulekile ekuvimbeleni i-neuronal nitric oxide synthase noma i-nNOS, ukuthi njengoba igama liphakamisa livezwa kuphela kuma-neuropathy nasenkabeni. Umsebenzi omkhulu we-nNOS ukuqapha nokulawula ithoni ye-vasomotor nokulawula umfutho wegazi ophakathi kanye nokugcinwa kwepulasitiki ye-synaptic kuma-neurons aphakathi.Ukuvinjelwa kwe-nNOS kokubili i-spermidine engapheli kanye ne-spermidine engaphandle kukholakala ukuthi inemiphumela yokuvikela, kufaka phakathi imiphumela elwa nokudangala. Ngaphezu kwalokho, ukuvinjelwa kwe-NNOS kunesibopho sokwehla okukhulu kokukhubazeka kwemisipha nokuwohloka kwama-spinal neurons okwenza lo msebenzi we-spermidine umsebenzi wokuvikela.
I-Spermidine, kanye namanye ama-polyamines, ikhonjisiwe ukuthi inomphumela ofanayo kumjikelezo weseli njengezinto zokukhula futhi ezisekela umsebenzi wazo omkhulu; autophagy nokuphila isikhathi eside. Ngaphezu kwalokho, i-spermidine ibophezela kumakhemikhali ahlukahlukene ukuxhasa imisebenzi ehlukile yenhlanganisela.
Ukusetshenziswa kwe-Spermidine Powder
I-Spermidine powder isetshenziswa njengesengezo ukuvikela izinhlobo ezahlukahlukene zomdlavuza, ikakhulukazi i-hepatocellular carcinoma kanye ne-fibrosis yesibindi. Iningi labantu likhetha ukuthatha i-spermidine powder njengesengezo ngenxa yekhono layo lokungagcini nje ngokuthuthukisa impilo ende kepha nangenxa yemiphumela yokuvikela yenkomponi.Izinzuzo ze-Spermidine Powder njenge-Supplement
Ukusetshenziswa kukaSpermidine njengesengezo kusetshenziswe nje muva nje kepha kuye kwasekelwa kakhulu ngocwaningo lwesayensi olutholile ukuthi lunezinzuzo eziningi emzimbeni womuntu. Ezinye izinzuzo eziyinhloko ze-spermidine powder njengesengezo yilezi:Imemori ethuthukisiwe nomsebenzi wokuqonda othuthukisiwe
Ukusetshenziswa kwe-spermidine powder kuhlotshaniswa nezakhiwo ze-neuroprotective yize lokho kungesona isici esiyinhloko esibhekele ukuthandwa okukhulayo kwenhlanganisela. Umphumela omuhle weSpermidine ebuchosheni nasekuqondeni kungumphumela wezinto zawo zokulwa nokuvuvukala ezivimbela ukuvuvukala kuma-neurons, yingakho kunciphisa izehlakalo zezifo eziningana ze-neurodegenerative njengeParkinson's Disease kanye ne-Alzheimer's Disease.Ucwaningo lwakamuva lugxile ekutadisheni umphumela wale polyamine ethile njengoba ama-polyamines angaba nemiphumela yomzimba yokuvikela kanye ne-neurotoxic. I-Spermidine yafundwa kumamodeli ezilwane ezinenkinga ye-neurodegenerative, ikakhulukazi i-neurodegeneration ngenxa yokuthukwa kwe-hypoxic-ischemic. Kutholakale ukuthi lokhu kuhlambalaza kubangele ukuvuvukala ngokuncipha kwezenzo ze-nitric oxide ebuchosheni. Kodwa-ke, ukusetshenziswa kwe-spermidine kuholele ekwehliseni ukuvuvukala njengoba kutholakale ukuthi kukhulisa i-enzyme, i-nitric oxide synthase ebuchosheni ebaluleke kakhulu ekwakhiweni kwe-nitric oxide, futhi ekugcineni, ukwelashwa kokuvuvukala. Lolu cwaningo luye lwafakazela imiphumela elwa nokuvuvukala kwe-spermidine nomlandeli wayo, i-spermine in vivo kumamodeli wezilwane.
Ucwaningo olufanayo lwenziwa ezinhlobonhlobo zezilwane ezinokukhubazeka kwezimoto nokwehla kwamazinga e-dopamine, ngenxa yokuchayeka ku-rotenone. Ukuvezwa kwe-Rotenone kulezi zinhlobo kubangela ukusilela kwezimoto okufana nokushoda kwezimoto okubonwa kubantu abaphethwe yisifo sikaParkinson. Ososayensi abenza lolu cwaningo bathole ukuthi i-spermidine inezakhi zokulwa ne-antioxidant ezisiza ukutakula ama-dopaminergic neurons athintwe yi-rotenone kumagundane ngenkathi futhi elwa nemiphumela yama-cytokines ahlaselayo kanye nengcindezi ye-oxidative. Lezi zingcindezi ziholela ekulimaleni kwama-neurons futhi ziholele ekwehleni okuphawulekayo kwama-neurotransmitters afana ne-serotonin, norepinephrine, ne-dopamine.
Ukusetshenziswa kweSpermidine kusindise la ma-neuron ezinhlobonhlobo zezilwane futhi kwaguqula ukusilela kwezimoto okubangelwa ukuvezwa kwe-rotenone, yingakho, kufakazela umbono wokuthi i-spermidine inezinto ezingavikeleki.
Ngokufanayo, kwenziwa ucwaningo lokuhlaziya imiphumela ye-spermidine yokudla ekusebenzeni kwengqondo. Kuyiqiniso elaziwayo ukuthi ukuguga kunomthelela omubi ekusebenzeni kwengqondo, noma kunjalo, kucatshangelwa ukuthi le miphumela ingaphikiswa ngokusetshenziswa kwezithako ze-spermidine powder.
Lapho kufundwa izinhlobo zezilwane ezinikezwe izithasiselo ze-spermidine, kutholakale ukuthi ingawela umgoqo wegazi nobuchopho futhi inyuse umsebenzi we-hippocampal nomsebenzi we-mitochondrial ebuchosheni. Lokhu kubaluleke kakhulu njengoba i-hippocampus ibalulekile ekwakhekeni kwenkumbulo nasekuqondeni, futhi nokwenza ngcono ukusebenza kwayo kungasiza kakhulu ekulweni nokuwohloka komzimba nokusebenza komzimba kwe-hippocampal.
Ngokuyinhloko, i-spermidine inezakhiwo ezilwa nokuvuvukala kanye ne-antioxidant kanye namandla okuwela umgoqo wegazi-wobuchopho ovumela ukuthi ube yi-ejenti yokuvikela umzimba emzimbeni womuntu.
Izakhiwo Zokulwa Nokuguga ezine-Autophagy Ekhuphukile
I-Spermidine iyinhlanganisela etholakala ngokwemvelo emzimbeni womuntu edlala indima ebalulekile esikhathini eside samaseli. Ibophezela kwi-DNA, i-RNA, namanye ama-molecule akhokhiswa kahle ayivumela ukuthi ibambe iqhaza ezinhlelweni eziningi zemethabolikhi. Imiphumela yalezi zinqubo ithuthukisa ukukhula kwamaseli, ukwanda kwamaseli, nokulwa nokuguga komzimba. Kodwa-ke, ayikwazi ukulwa nemiphumela yokuguga nokufa kwamangqamuzana njengoba umuntu eguga ngoba amazinga e-spermidine aqala ukwehla kusuka eminyakeni yobudala obuphakathi.Ukuguga kuyinqubo eyinkimbinkimbi yezakhi zofuzo eyenzeka ekuphenduleni izingcindezi ezahlukahlukene kanye nesikhuthazi esingadala ukufa kweseli. Ukusetshenziswa kwezithako zokudla ze-spermidine powder kukholakala ukuthi kunomphumela wokulwa nokuguga emzimbeni womuntu ngamandla ayo okwenza i-autophagy. Kalula nje, i-autophagy inqubo yeselula, okuthi uma ihunyushwa isho ukuthi 'ukuzidlela wena'. Le nqubo ibhekele ukugaywa kwama-organelles namaprotheni angasebenzi kahle, ngokulandelana, okuholela ekubhujisweni kwamaseli angasakwazi ukwenza imisebenzi edingekayo. Yize umsebenzi wayo ubonakala uyingozi, i-autophagy inomthelela wokuvikela kumaseli njengoba isusa amaseli angasasebenzi.
Ukusetshenziswa kwe-spermidine trihydrochloride powder kuhlotshaniswa nokukhuphuka kokuzenzakalela emzimbeni womuntu okusiza ezinhlelweni zokulwa nokuguga njengoba kususa amaseli angasebenzi, kuthuthukisa ukukhiqizwa kwamaseli amasha futhi asebenzayo. Lokhu kuvuselelwa kwamaselula kubalulekile ukuvimbela amaseli angasebenzi kahle ukuba angahlali emzimbeni okuholela emiphumeleni eyihaba yokuguga.
Ukwenziwa kwe-autophagy yi-spermidine powder nakho kudlala indima kumasosha omzimba, ikakhulukazi kuma-T cell. Ucwaningo lwakamuva luthole ukuthi ama-autophagy boosting agents, njenge-spermidine, angasiza ekuthuthukiseni impendulo yeziguli ezindala emithini yokugoma. Abaphenyi bahlose ukudlulisa lolu lwazi ezikhungweni zokugoma futhi banethemba lokwenza ukusetshenziswa kwe-spermidine yokudla kube umthetho olandelwayo weziguli ezindala ezigonywayo.
Ngaphandle kokuzilimaza, i-spermidine nayo inezinto ezilwa nokuguga ngenxa yezinye izinqubo ezisiza ukuvimbela izimpawu eziyisithupha kweziyisishiyagalolunye zokuguga emzimbeni womuntu. Njengonyaka owodwa, amaseli ama-stem alahlekelwa amandla awo okuhlukanisa abe yizinhlobo zamaseli ezahlukile eziye zafa, zafuduka, noma zalahlekelwa amakhono azo okusebenza. Lokhu kubangela ushintsho olungalungiseki emzimbeni womuntu njengokumpunga kwezinwele futhi yonke inqubo ibizwa ngokuthi ukukhathala kweseli. Lesi sici sokuguga sivinjelwe noma silwa nezithako zokudla ze-spermidine powder ezingakhuphula impilo ende yamaseli we-stem.
Ukuguqulwa kwe-Epigenetic kungenye yezimpawu zokuguga ezibhekisa kuzinguquko ezingxenyeni zofuzo zeseli kanye nokwakheka kweseli kanye ne-physiology ngenxa yokuvezwa kwezimo ezahlukahlukene zemvelo. Lobu buthi bezemvelo benza ushintsho kumaseli athinta kabi iseli elibangela ukuguga kwamangqamuzana ekugcineni, nokufa kwamaseli. Lesi sici siphinde silwe nokusetshenziswa kwe-spermidine njengoba kwaziwa ngokukhuthaza ukuvuselelwa kwamaselula.
Njengoba amaseli ekhula, aqondisa amandla awo amaningi ekuzilondolozeni okuholela ekushintsheni ukuxhumana okungekuhle kwangaphandle kwamaseli njengoba iseli lizolimaza amanye amaseli azama ukugcina impilo yawo futhi avuselele impilo ende. Kodwa-ke, lokhu, ngokuhamba kwesikhathi, kungaba nomthelela omubi kwimpilo yezicubu nezitho zomzimba, okutholakala njalo kubantu asebekhulile. Kodwa-ke, ukusetshenziswa kwe-spermidine kukholakala ukuthi kunciphisa ukuguqulwa kokuxhumana phakathi kwamaseli ukukhuthaza impilo ende yawo wonke amaseli, ngaphandle kokulimaza amanye amaseli akulesi sicubu.
Amaprotheni adlala indima ebalulekile kumaseli futhi ayadingeka kuzo zonke izinqubo ze-metabolic ukuthi zenziwe kahle. Amaprotheni adinga ukwakhiwa kahle emzimbeni ukuqinisekisa ukusebenza kahle komzimba kanye nokugcinwa kwe-homeostasis. Ngokukhula, amaprotheni alahlekelwa amandla awo okubambelela kusakhiwo sawo esiwavumela ukuthi enze imisebenzi ethile. Izingcindezi zemvelo zithinta lawa maprotheni nezindlela eziholela ekukhiqizweni nasekugcinweni kwalezi zinhlaka zamaprotheni. Lokhu kubhekiswa njengokulahleka kwe-proteostasis futhi luphawu olubalulekile lokuguga.
Isikhathi sokuphila seseli siyaphela futhi iseli lingena esikhathini sokuthamba lapho ama-telomeres esitokisi emfishane kakhulu ukuthi iseli lingakwazi ukuhlukanisa futhi. AmaTelomere aqhubeka nokunciphisa njengoba iseli lihlukana futhi ekugcineni lifinyelela ngosayizi omncane kakhulu ukuvumela ukwahlukana okwengeziwe kwamaseli, okuholela ekuthuleni kwe-telomere. Ngemuva kwalokhu, iseli alikwazi ukuhlukana futhi ekugcineni lizofa. Ukuncishiswa kweTelomere kuwuphawu olubalulekile lokuguga okuye kwafundwa futhi kwacwaningwa kahle ekwakhiweni kwamakhemikhali alwa nokuguga. I-Spermidine itholakala emzimbeni futhi inesibopho sokuphikisana nemiphumela yokuthula kwe-telomere, okuvumela amaseli ukuthi ahlukane ngokukhululeka isikhathi eside.
I-Spermidine ithuthukisa imisebenzi ye-mitochondrial futhi inciphise umphumela wokuxineka kwe-oxidative emzimbeni. Lokhu kungenye yezimpawu zokuguga ezingaphikiswa ngokusebenzisa izithako zokudla ze-spermidine powder.
· Ivimbela Izinhlobo Ezithile Zomdlavuza Ekuthuthukiseni
I-Spermidine kukholakala ukuthi inemiphumela elwa neoplastic njengoba kutholakele ukuthi abantu abathatha i-spermidine banokwehla kwengozi yokuthola i-hepatocellular carcinoma kanye nesimo sayo esandulele, isibindi i-fibrosis. Ucwaningo lwakamuva luthole ukuthi i-spermidine iyakwazi ukumisa i-fibrosis yesibindi ukuthi ingakhuli ngisho nakumamodeli wezilwane abekade echayeke ngenkuthalo kumakhemikhali anekhono lokukhiqiza i-fibrosis yesibindi.Ucwaningo lokubuka luye lwathola ukuthi ukusetshenziswa kwe-spermidine kunamandla okuvimbela umdlavuza wekoloni, noma ngabe olunye ucwaningo ludinga ukwenziwa ngaphambi kokuthi lufakwe kumihlahlandlela yokwelashwa nokuvimbela.
Ngaphezu kwalokho, kutholakale ukuthi ukusetshenziswa kwe-spermidine ezigulini zamakhemikhali ezelashelwa umdlavuza wesikhumba nomdlavuza wesisu kusize ekuthuthukiseni imiphumela yokwelashwa nokwenza ngcono izinto ezibikezela umdlavuza.
Gcina isigqi se-Circadian esifanele
Izithako zeSpermidine zivame ukukhangiswa njengokulala ukuqala nokugcina imikhiqizo ngenkathi ibuye igxile ekwenzeni ngcono isigqi se-circadian. Ucwaningo olwenziwe ezinhlobonhlobo zezilwane luthole ukuthi amagundane amadala, anezinga eliphansi le-spermidine emzimbeni wawo, anesigqi esisheshayo se-circadian esivame ukukhula njengezinkinga zokulala. Lapho kulekelelwa nge-spermidine powder, la magundane amadala atholakala ukuthi anesigqi se-circadian esisebenza kakhulu ngomjikelezo ojwayelekile we-circadian.Ukuhlobisa izinwele, izipikili nesikhumba
I-Spermidine ivuselela amaseli futhi ikhuthaze ukukhula kwamaseli okunempilo okuguqula imiphumela yokuguga esikhunjeni, ezinweleni nasezipikili. Ukuguga kuba nomthelela ekubukekeni kwesikhumba, kuthi isikhumba esigugile sivele sishwabene futhi sigugile ngokuthamba. Le miphumela ingaguqulwa kusetshenziswa izithasiselo ze-spermidine ezinconyelwe ngenkuthalo ukwenza ubuhle bezinwele, izipikili nesikhumba.Yikuphi Ukudla okunothile ku-Spermidine Powder?
I-Spermidine itholakala ngokwemvelo emithonjeni eminingi yokudla, ikakhulukazi leyo engeyokudla kwaseMedithera. Imithombo yokudla ye-spermidine ishiwo ngezansi:- Durian
- Amagciwane kakolweni
- Upelepele Ohlaza Okotshani
- I-broccoli
- Ikhowe
- Ukholifulawa
- Ushizi (izinhlobo ezahlukahlukene zinokuqukethwe okuhlukile kwe-spermidine)
- Natto
- Amakhowe eShiitake
- Amaranth okusanhlamvu
Kuyini iSpermidine Wheat Germ Extract?
I-Spermidine njengesengezo sokudla itholakala ku-germ yegciwane ecebile nge-spermidine. Ukwenza lesi sithasiselo esitshalweni sikakolweni, i-kernel kakolweni iyelashwa ukukhipha i-spermidine yayo ku-endospore. Ukukhishwa kukigramu kakolweni ovutshiwe kukhiqizwa ngokwelapha okukhishwe ku-kernel kakolweni ngokukhipha imvubelo. Eyaziwa nangokuthi i-Fermented Extract Of Wheat Germ, i-FWGE, i-MSC, i-Triticum Aestivum Germ Extract, ne-Triticum Vulgare Germ Extract, lo mkhiqizo yilokho okunikeza izithako zokudla ze-spermidine nge-spermidine.Ukusetshenziswa kweSpermidine Wheat Germ Extract
Ukukhishwa kwegciwane lengqolowa yespermidine kuyanconywa kubantu abafuna ukuguqula imiphumela yokuguga emzimbeni wabo, njengokumpunga kwezinwele, imibimbi yesikhumba, nokwehla kokukhiqizwa kwamandla. Okunye ukusetshenziswa kwe-FGWE kufaka:- Ukushiswa yilanga: Njengoba i-spermidine ikwazi ukukhuthaza ukukhula kwamangqamuzana, ukwanda, nokuvuselelwa, kukholakala ukuthi amaseli alinyazwe ukuvezwa kwe-UV angazuza emiphumeleni ye-spermidine. Lawa maseli afakwa enkambisweni yokuzimela ngenxa yokusebenzisa i-spermidine, okuzoholela ekutheni kukhiqizwe amaseli amasha ukwelapha ukushiswa yilanga.
- Ukuvimbela umkhuhlane ezigulini zamakhemikhali: i-spermidine ibamba iqhaza elibalulekile emasosheni omzimba ngokusebenzisa izakhiwo zayo ezizenzekelayo, futhi yilezi zakhiwo ezisiza i-spermidine germ wheat uketshezi oluyimpuphu ukukhuthaza ukubhujiswa kwamangqamuzana awonakele ngamakhemikhali nokwandisa ukwanda kwamaseli amasha. Lokhu kusiza ukuvuselela ama-T cell aphilile futhi asebenzayo emzimbeni asiza lezi ziguli ukulwa nezifo eziphindaphindayo.
- Ukuphathwa kokuphazamiseka komzimba: I-Spermidine inezakhiwo ezilwa nokuvuvukala ezisiza ekuphathweni kwezifo ezizimele zomzimba ezinezici ezivuvukala.
Imiphumela emibi yokusetshenziswa kwe-Spermidine Powder
I-Spermidine iyi-polyamine etholakala ngokwemvelo emzimbeni, okungaphezulu kwayo okungenayo imiphumela emibi emzimbeni womuntu. Kodwa-ke, amazinga aphansi e-spermidine emzimbeni ahlobene nokuguga kusenesikhathi, ukwehla kwenkumbulo nokusebenza kwengqondo, kanye nokwehla kokuqina kwesakhiwo nobuqotho besikhumba. Kubuye kube nomphumela wokukhubazeka komsebenzi we-mitochondrial obese wenza ihaba ngemiphumela yokuguga emzimbeni.Izithako zeSpermidine ezenziwa kusetshenziswa ikhwalithi ephezulu yegciwane lesikhumba futhi ngokulandela yonke imihlahlandlela yokuphepha kanye nenqubo elandelwayo futhi kubhekwe njengokuvikelekile ukusetshenziswa kwabantu. Lezi zithasiselo zifundisiswe kahle futhi akukho miphumela emibi eseyitholakele, yingakho kudinga ukuthi kwenziwe olunye ucwaningo. Kubalulekile ukuqaphela ukuthi abukho ubuthi be-spermidine powder obusabikiwe
Kungani Kufanele Ukhethe I-Spermidine Powder Manufacturing Factory Yethu?
I-Spermidine powder iyinhlanganisela ezinzile etholakala nasemzimbeni. Kwifektri yethu yokukhiqiza, i-spermidine powder ikhiqizwa endaweni yokucwaninga enobuchwepheshe, eyinyumba ukuqinisekisa ukuphepha komkhiqizo. Umkhiqizo wenziwa ngokulandela imihlahlandlela kanye nezinqubomgomo zokuphepha ukuqinisekisa izinzuzo ezinkulu zesithako se-spermidine ngenkathi kunciphisa nethuba lokungcola noma ukusabela kwenhlanganisela neminye imikhiqizo. Ngaphezu kwalokho, imikhiqizo ihlolwa ilebhu ngemuva kokukhiqizwa ukuqinisekisa ukuphepha kwayo, ukusebenza kwayo namandla. Noma imuphi umkhiqizo we-spermidine ongakudlulisi lokhu kuhlolwa awufakwanga futhi awulungiselelwe ukuthengiswa kepha kunalokho uyabuyiselwa emuva, futhi eminye imikhiqizo eqenjini elifanayo ifakwa kuqeqesho olunzulu ukuqinisekisa ukuthi ayikho inkinga ngekhwalithi ye-spermidine powder.I-Spermidine powder iyatholakala ngokuphelele efektri yethu, yize ithengiswa kuphela ngezinjongo zocwaningo nezentuthuko, noma ngokusetshenziswa kwayo emkhakheni wemithi yokwelapha. I-Spermidine ingumuthi ophakathi nendawo owenza imithi kanye ne-substrate ebalulekile ekhemistry yezokwelapha neyebhayoloji. Ngalezi zinhloso, i-powder ephezulu ye-Spermidine iyadingeka, etholakala efektri yethu yokukhiqiza i-Spermidine.
I-Spermidine powder evela ezikhungweni zethu zokukhiqiza iyatholakala ukuthengwa ngamaphakeji ahlukile nezimo, ngokuya ngezidingo zabathengi. Iphakheji ngayinye inelebula enosuku lokuhlolwa nosuku lokukhiqiza, ukuqinisekisa ukuhlolwa kokulawulwa kwekhwalithi okulula nezinsizakalo zokulandelela.
Izikhombo:
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- Isilingo sokuhlola izidakamizwa ezibhekiswe e-Alzheimer's sikhombisa imiphumela yokulwa nokuguga ”(Press release). ISalk Institute. 12 Novemba 2015. Ibuyiswe ngoNovemba 13, 2015.
- Abaphenyi bakhomba umgomo wamangqamuzana we-J147, osondela ekuhlolweni kwemitholampilo ukwelapha isifo i-Alzheimer's ”. Kubuyiswe ngo-2018-01-30.
- Ukulungiswa Kwezinguquko Ze-Alzheimer Disease Neuropathologic With Isimo Sokuqonda: Ukubuyekezwa Kwezincwadi UPeter T. Nelson, u-Irina Alafuzoff, u-Eileen H. Bigio, uConstantin Bouras, uHeiko Braak, uNigel J. Cairns, uRudolph J. Castellani, uBarbara J. Crain, uPeter UDavies, Kelly Del Tredici, Charles Duyckaerts, Matthew P. Frosch, Vahram Haroutunian, Patrick R. Hof, Christine M. Hulette, Bradley T.Hyman, Takeshi Iwatsubo, Kurt A. Jellinger, Gregory A. Jicha, Enikö Kövari, Walter A . Kukull, James B. Leverenz, Seth Love, Ian R. Mackenzie, David M. Mann, Eliezer Masliah, Ann C. McKee, Thomas J. Montine, John C. Morris, Julie A. Schneider, Joshua A. Sonnen, Dietmar R. Thal, John Q. Trojanowski, Juan C. Troncoso, Thomas Wisniewski, Randall L. Woltjer, Thomas G. Beach J Neuropathol Exp Neurol. Umbhalo wesandla; itholakala ku-PMC 2013 Jan 30. Ishicilelwe efomini lokugcina elihleliwe njenge: J Neuropathol Exp Neurol. UNhlaba wezi-2012; 71 (5): 362--381. i-doi: 10.1097 / NEN.0b013e31825018f7
