Imikhiqizo

I-Olivetol powder (500-66-3)

I-Olivetol yingxube yemvelo evela ngokwendalo. Itholakala ezinhlotsheni ezithile zama-lichens futhi ingakhishwa kalula. I-5-Pentylresorcinol nayo ikhiqizwa izinambuzane eziningi, kungaba nge-pheromone, i-repellent noma i-antiseptic. Isitshalo se-cannabis ngaphakathi sikhiqiza umkhiqizo ohlobene ne-olivetolic acid (OLA), okwakufakazelwa ukuthi lesi sitshalo sisebenzisa i-biosynthesize umkhiqizo we-psychoactive product tetrahydrocannabinol (THC).

Ukwakha: Ukukhiqizwa Kweqoqwana
Iphakheji: 1KG / isikhwama, 25KG / isigubhu
I-Wisepowder inamandla okukhiqiza nokuhlinzeka ngobuningi obukhulu. Konke ukukhiqizwa ngaphansi kwesimo se-cGMP kanye nohlelo oluqinile lokulawula ikhwalithi, yonke imibhalo yokuhlola nesampula etholakalayo.

Ividiyo ye-Olivetol powder (500-66-3)

 

 

Imininingwane ye-Olivetol powder (500-66-3)

Igama I-Olivetol (3,5-hydroxypentylbenzene) powder
CAS 500-66-3
Ukuhlanzeka 98%
Igama lamakhemikhali I-Olivetol
omqondofana I-3,5-Dihydroxyamylbenzene; I-5-n-Amylresorcinol; I-5-n-Pentylresorcinol; 1,3-Dihydroxy-5-pentylbenzene; I-5-Pentyl-1,3-benzenediol;
Formula Yamamolekhula C11H16O2
isisindo Yamamolekhula 180.2435
I-Melting Point I-46-48 ° C (ivuliwe.)
InChI Key I-IRMPFYJSHJGOPE-UHFFFAOYSA-N
Ifomu Eqinile
ukubukeka onsomi okhanyayo kuya kwekristalu emsundu
Ukuphila okungaphelele /
solubility I-soluble emanzini (ngokwengxenye engeyiyo), i-chloroform, ne-methanol.
isitoreji Isimo Esigcini esomile nesingene komoya; hlukana nokukhanya kwelanga; gwema umlilo; gwema umswakama.
Isicelo I-Olivetol ihlanganiswe i-biosynthesized yi-polyketide synthase-hlobo reaction kusuka ku-hexanoyl-CoA kanye nama-molecule amathathu e-malonyl-CoA yi-aldol condensation ye-tetraketide Lesisemkhatsini.
Idokhumenti yokuhlola Iyatholakala

 

I-Olivetol powder (500-66-3) Incazelo Okujwayelekile

I-Olivetol yayisetshenziswa njenge-molecule yethempulethi ekuhlanganiseni i-polymer (MIP) yama-molecule. Iphinde yasetshenziswa njenge-inhibitor ye (S) -mephenytoin 4′-hydroxylase umsebenzi we-recombinant CYP2C19.

I-Olivetol isetshenziswa ngezindlela ezahlukahlukene ukukhiqiza ama-analog zokwenziwa we-THC.full cation edingekayo] Enye indlela enjalo ukusabela kwe-olivetol ne-pulegone. EPiHKAL, u-Alexander Shulgin ubika indlela yokuqola yokukhiqiza umkhiqizo ofanayo ngokuletha i-olivetol yokusabela kanye namafutha abalulekile e-orange lapho kukhona i-phosphoryl chloride.

Indlela yokwakheka kwe-THC uqobo iqukethe ukusabela okuphakathi kwe-olivetol ne-Δ2-carene oxide

 

Umlando we-Olivetol powder (500-66-3)

I-Olivetol ihlanganiswa nge-biosynthesized by a polyketide synthase-type reaction from hexanoyl-CoA kanye nama-molecule amathathu we-malonyl-CoA nge-aldol condensation ye-tetraketide ephakathi. Ngo-2009, uTaura et al. ukwazile ukuhlanganisa uhlobo lwe-III PKS olubizwa nge-olivetol synthase (OLS) kusuka kwaCannabis sativa. Le PKS iphrotheni elenziwa njenge-homodimeric eliqukethe i-385 amino acid polypeptide enesisindo samangqamuzana angama-42,585 Da anokufana okulandelanayo okuphezulu (60-70%) ubunikazi bokutshala ama-PKS.

 

Isicelo se-Olivetol powder (500-66-3)

1, Isetshenziswe njengemboni yezemithi.

2, Isetshenziswe njenge-Organic Intermediate.

I-3, Isetshenziswe njengokunqunywa kwe-lipopolysaccharides, i-carrageenan ne-sialic acid.

 

I-Olivetol powder (500-66-3) Ucwaningo olwengeziwe

Ukukhiqizwa, ukutholakala, kanye / noma ukusatshalaliswa kwe-olivetol akukho emthethweni kunoma yiliphi izwe; kodwa-ke e-United States, kungumbuso we-DEA obukelwe ngaphambili.

 

Inkomba ye-Olivetol powder (500-66-3)

  • Kumano, T., et al: Bioorg. UMedi. I-Chem., 16, 8117 (2008), Appendino, G., et al .: J. Nat. Prod., 71, 1427 (2008), Sampietro, D., et al .: Khemikhali Yezokudla., 115, 1170 (2009),
  • . Jiang R, et al. ICannabidiol ingukuvimbela okunamandla komsebenzi wokukhuthazeka we-cytochrome P450 2C19. Izidakamizwa Metab Pharmacokinet. 2013; 28 (4): 332-8.
  • . I-Yamaori S, et al. I-Cannabidiol, i-phytocannabinoid enkulu, njenge-inhibitor enamandla ye-atypical ye-CYP2D6. Izidakamizwa Zemithi Yezidakamizwa. 2011 Nov; 39 (11): 2049-56.

 

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